REAL-WORLD CLINICAL OUTCOMES WITH FIRST-LINE SYSTEMIC TREATMENT AND AVELUMAB MAINTENANCE IN US PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CARCINOMA: THE SPEAR BLADDER-II STUDY

Avelumab first-line maintenance (1LM) is approved for patients with locally advanced or metastatic urothelial carcinoma (la/mUC) who do not have disease progression after platinum-based chemotherapy (PBC).This retrospective study describes real-world treatment patterns and clinical outcomes in patients with la/mUC who initiated first-line (1L) syst

Hunting for wildlife in Way Kambas National Park (WKNP) is one of the leading causes of humans and animal conflict.So far, patrol activities are still considered less than optimal because of the decline in animal populations due to frequent hunting.This study aimed to analyze the findings of forest ranger patrols in protecting wild animals from moe

Abstract Effective transfer learning for molecular property prediction has shown considerable strength in addressing insufficient labeled molecules.Many existing methods either disregard the quantitative relationship between source and target properties, risking negative transfer, or require intensive training on target tasks.To quantify transferab

Introduction Electroconvulsive therapy (ECT) is considered the most effective treatment for catatonia regardless its underlying condition.The rigid fixed posture and immobility observed in catatonia e. cuarenta cerveza may lead to several clinical complications, of which, pulmonary embolism (PE) is one of the most severe.The rapid improvement of th

IntroductionThe collection and process of human brain activity signals play an essential role in developing brain-computer interface (BCI) systems.A portable electroencephalogram (EEG) device has become an important tool for monitoring brain activity and diagnosing mental diseases.However, the miniaturization, portability, and scalability of EEG re